RRML - Congenital Nephrotic Syndrome of Finnish Type. A Report of Two Cases
AMLR

ISSN online: 2284-5623

ISSN-L: 1841-6624

Rejection rate (2020): 75%

Română English


Journal Metrics

Impact Factor 0.5
Five Year Impact Factor 0.5
JCI 0.12


Advanced search


Top 10 downloaded articles
- February 2024 -
 
Anti-thyroid peroxidase (TPO) ... 18
Romanian Review of Laboratory ... 17
Recomandarea comună EFLM-COLA... 13
Approaching Risk Management in... 12
Identification of shared hub g... 12
Challenges in prophylactic the... 12
Monocyte to high-density lipop... 9
Atellica CH 930 chemistry anal... 8
Setting up an own laboratory p... 7
Understanding the key differen... 7

Log in

Concept, Design & Programming
Dr. Adrian Man

   
 
Nr. 17(4)/2009
XML
TXT

Congenital Nephrotic Syndrome of Finnish Type. A Report of Two Cases

Carmen Duicu, Eva Kiss, Claudia Bănescu, Virginia Bodescu, Zsuzsanna Moreh, Emöke Horvath


Abstract:

Congenital nephrotic syndrome of the Finnish type (CNSF) is a rare autosomal recessive disease with high infant mortality without aggressive treatment. CNSF is characterized by massive in utero proteinuria and nephrosis at birth. The majority of cases are caused by genetic defects in the components of the glomerular filtration barrier, especially nephrin and podocin. Congenital nephrotic syndrome (CNS) may also be a part of a more generalized syndrome or caused by a perinatal infection. Immunosuppressive medication is not helpful in the genetic forms of CNS, and kidney transplantation is the only curative therapy. This paper describes the clinical features and outcome of the last 2 patients from 6 with CNSF who have been admitted to Pediatric Clinics from Târgu Mures in the last 15 years.

Keywords: congenital nephrotic syndrome,proteinuria

 
  PDF Download full text PDF
(568 KB)
     
 
How to cite
Duicu C, Kiss E, Bănescu C, Bodescu V, Moreh Z, Horvath E. Congenital Nephrotic Syndrome of Finnish Type. A Report of Two Cases . Rev Romana Med Lab. 2009;17(4):43-9