RRML - Cardiovascular risk factors incidence in patients with aortic prostheses with and without coronary artery disease
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Dr. Adrian Man

   
 
Nr. 4(3)/2006
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Cardiovascular risk factors incidence in patients with aortic prostheses with and without coronary artery disease

Dana Velimirovici, Maria Rada, Delia Berceanu-Văduva, Simona Drăgan, M. Berceanu-Văduva, D. Gaiţă, F. I. Cobzariu, C. A. Sarău, Stela Iurciuc, Silvia Mancaş


Abstract:

Objectives: The aim of this work to assess the incidence of cardiovascular risk factors (CRF) in patients with aortic prostheses for aortic degenerative stenosis with and without coronary artery disease (CAD). We enrolled 96 patients with aortic valvular prostheses: 20 patients (20.83%) had also CAD with concomitant myocardial revascularization. Male patients were predominant (63.54%); mean age 68±7 years. We studied the incidence of CRF: BP ≥ 140/90mmHg; BMI ≥ 30kg/m2; TC ≥ 200mg/dl or undergoing pharmacological treatment for dislipidemia; fasting plasma glucose ≥ 126mg/dl or previous diagnosed diabetes mellitus; smoking or ex-smoker state. Patients with aortic degenerative stenosis were predominant (group A=79.1); aortic degenerative stenosis was associated with CAD in a 20.83% cases (group B). In group B, CABG with a single graft was predominant (50%), with 2 grafts in 40% cases and with 3 grafts in 10%. The incidence of risk factors show that in aortic degenerative lesions with CAD there was a higher prevalence of hypercholesterolemia 40% (p=0.0001), hypertensions 35% (p=0.004), obesity 30% (p=0.007) and diabetes mellitus 15% (p=0.05). There were no significant differences regarding the ex-smoker state. In group B, patients with ≥ 3 risk factors were predominant (55%) and in group A those with 1-2 risk factors (51.31%). Major CRF for atherosclerosis are the same as those implied in aortic degenerative stenosis development. There is a higher incidence of CRF if aortic degenerative stenosis is associated with CAD. Risk factors aggregation is significant in those with both conditions.

Keywords: cardiovascular risk factors,aortic degenerative stenosis,aortic prostheses,coronary artery disease

 
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How to cite
Velimirovici D, Rada M, Berceanu-Văduva D, Drăgan S, Berceanu-Văduva M, Gaiţă D, et al. Cardiovascular risk factors incidence in patients with aortic prostheses with and without coronary artery disease. Rev Romana Med Lab. 2006;4(3):29-35