RRML - Genetic risk factors for thrombosis and complications during pregnancy
AMLR

ISSN online: 2284-5623

ISSN-L: 1841-6624

Rejection rate (2020): 75%

Română English


Journal Metrics

Impact Factor 0.5
Five Year Impact Factor 0.5
JCI 0.12


Advanced search


Top 10 downloaded articles
- February 2025 -
 
Association of neutrophil-to-l... 16
A comparative study of legisla... 16
Correlation between fecal biom... 14
COVID-19 or systemic lupus ery... 12
CALLY index, but not HALP scor... 12
Romanian Review of Laboratory ... 10
Correlations of vascular cogni... 9
A diagnostic classifier for os... 8
Investigation of cytokine chan... 6
Platelets and Infections... 4

Log in

Concept, Design & Programming
Dr. Adrian Man

   
 
Nr. 1(1)/2005
XML
TXT

Genetic risk factors for thrombosis and complications during pregnancy

Domniţa Crişan, Ruxandra Alecsandrescu


Abstract:

Thrombembolism is a multicausal disease in which both acquired and genetic risk factors and also their interaction play a role. Inherited thrombophilia is now demonstrated to be a multigenic disease; the most common genetic risk factors are factor V Leiden and the prothrombin mutations. Prior to the discovery of these mutations, three less common genetic risk factors had been reported in thrombophilia families: antithrombin, protein C and protein S deficiencies. Dysfibrinogenemias are the least common causes of inherited thrombophilia. The risk of venous thrombosis associated with pregnancy is further increased in women with inherited thrombophilia, resulting in higher incidence of thromboembolic complications during pregnancy and puerperium and also higher incidence of fetal loss, fetal growth retardation, preeclampsia and abruptio placentae. For management and prevention of thrombotic complication of pregnancy, testing for the genetic risk fac-tors have became indispensable.

 
  PDF Download full text PDF
(114 KB)
     
 
How to cite
Crişan D, Alecsandrescu R. Genetic risk factors for thrombosis and complications during pregnancy. Rev Romana Med Lab. 2005;1(1):48-51