RRML - Oxyphilic clear cell carcinoma of the ovary with a minor clear cell component- case report with emphasis on the morphological diversity and histogenesis

Main page
News
RJLabM Credits
Archive
- Current issue
- Ahead of print
- List of published issues
- 2024
  - Nr.4/2024
  - Nr.3/2024
  - Nr.2/2024
  - Nr.1/2024
  - Supplement 1/2024
- 2023
  - Nr.4/2023
  - Nr.3/2023
  - Nr.2/2023
  - Nr.1/2023
  - Supplement 1/2023
- 2022
  - Nr.4/2022
  - Nr.3/2022
  - Nr.2/2022
  - Nr.1/2022
  - Supplement 1/2022
- 2021
  - Nr.4/2021
  - Nr.3/2021
  - Nr.2/2021
  - Nr.1/2021
- 2020
  - Nr.4/2020
  - Nr.3/2020
  - Nr.2/2020
  - Nr.1/2020
  - Supplement 1/2020
- 2019
  - Nr.4/2019
  - Nr.3/2019
  - Nr.2/2019
  - Nr.1/2019
  - Supplement 1/2019
- 2018
  - Nr.4/2018
  - Nr.3/2018
  - Nr.2/2018
  - Nr.1/2018
  - Supplement 1/2018
  - Supplement 2/2018
  - Supplement 3/2018
- 2017
  - Nr.4/2017
  - Nr.3/2017
  - Nr.2/2017
  - Nr.1/2017
  - Supplement 1/2017
- 2016
  - Nr.4/2016
  - Nr.3/2016
  - Nr.2/2016
  - Nr.1/2016
  - Supplement 1/2016
- 2015
  - Nr.4/2015
  - Nr.3/2015
  - Nr.2/2015
  - Nr.1/2015
  - Supplement 1/2015
- 2014
  - Nr.4/2014
  - Nr.3/2014
  - Nr.2/2014
  - Nr.1/2014
  - Supplement 1/2014
- 2013
  - Nr.4/2013
  - Nr.3/2013
  - Nr.2/2013
  - Nr.1/2013
  - Supplement 1/2013
- 2012
  - Nr.4/2012
  - Nr.3/2012
  - Nr.2/2012
  - Nr.1/2012
  - Supplement 1/2012
- 2011
  - Nr.4/2011
  - Nr.3/2011
  - Nr.2/2011
  - Nr.1/2011
  - Supplement 1/2011
- 2010
  - Nr.4/2010
  - Nr.3/2010
  - Nr.2/2010
  - Nr.1/2010
  - Supplement 1/2010
- 2009
  - Nr.4/2009
  - Nr.3/2009
  - Nr.2/2009
  - Nr.1/2009
  - Supplement 1/2009
- 2008
  - Nr.4/2008
  - Nr.3/2008
  - Nr.2/2008
  - Nr.1/2008
  - Supplement 1/2008
- 2007
  - Nr.4/2007
  - Nr.3/2007
  - Nr.2/2007
  - Nr.1/2007
- 2006
  - Nr.4/2006
  - Nr.3/2006
  - Nr.2/2006
  - Nr.1/2006
- 2005
  - Nr.1/2005
Instructions for authors
Online applications
- Send an article
- Online payments
Editorial
About us
Links

ISSN online: 2284-5623

ISSN-L: 1841-6624

Rejection rate (2020): 75%

Journal Metrics

Impact Factor 0.5
Five Year Impact Factor 0.5
JCI 0.12

Top 10 downloaded articles - November 2024 -

Towards appropriate training f...	31
Recomandările naționale ale ...	28
Biomarkers of acute kidney inj...	23
A comprehensive review of glyc...	20
Agreement between different eG...	19
Investigation of cytokine chan...	19
Expressions of vascular endoth...	17
Role of Th1/Th2 imbalance medi...	16
Small patients, big challenges...	9
The frequency of EGFR gene mut...	8

Concept, Design & Programming
Dr. Adrian Man

Nr. 18(1)/2010

Oxyphilic clear cell carcinoma of the ovary with a minor clear cell component- case report with emphasis on the morphological diversity and histogenesis

Simona Stolnicu, Ovidiu Preda, Szabo Kinga, Sorin Andrei, Romeo Nicolau, Alina Nicolae, Francisco F. Nogales

Abstract:

This paper presents a case of oxyphilic clear cell carcinoma of the ovary in an old patient. Because of its histology and the association with peculiar patterns as hemosiderinic pigment, psammoma bodies, pseudo-papillary or follicular-spaces and grooved nuclei, this tumor is responsible for a significant proportion of differential diagnosis in ovarian pathology. Since ovarian clear cell carcinoma has a bad prognosis and is usually more resistant to systemic chemotherapy than other types, recognition of this entity from other primaries and metastatic oxyphilic cell tumors in the ovary is mandatory. The origin in endometriotic cysts or related lesions demonstrated by molecular biology and suggested in this case by the presence of hemorrhage and hemosiderin pigment may explain the good prognosis in early stages of the disease despite the fact that the tumor is poorly differentiated, grade three and always associated with atypia.

Keywords: clear cell carcinoma,ovary,oxyphilic cells

Download full text PDF
(831 KB)

Stolnicu S, Preda O, Kinga S, Andrei S, Nicolau R, Nicolae A, et al. Oxyphilic clear cell carcinoma of the ovary with a minor clear cell component- case report with emphasis on the morphological diversity and histogenesis. Rev Romana Med Lab. 2010;18(1):57-63