RRML - Fatal sepsis due to community-associated methicillin-resistant Staphylococcus aureus

RRML - Fatal sepsis due to community-associated methicillin-resistant Staphylococcus aureus – a case report

Main page
News
RJLabM Credits
Archive
- Current issue
- Ahead of print
- List of published issues
- 2024
  - Nr.4/2024
  - Nr.3/2024
  - Nr.2/2024
  - Nr.1/2024
  - Supplement 1/2024
- 2023
  - Nr.4/2023
  - Nr.3/2023
  - Nr.2/2023
  - Nr.1/2023
  - Supplement 1/2023
- 2022
  - Nr.4/2022
  - Nr.3/2022
  - Nr.2/2022
  - Nr.1/2022
  - Supplement 1/2022
- 2021
  - Nr.4/2021
  - Nr.3/2021
  - Nr.2/2021
  - Nr.1/2021
- 2020
  - Nr.4/2020
  - Nr.3/2020
  - Nr.2/2020
  - Nr.1/2020
  - Supplement 1/2020
- 2019
  - Nr.4/2019
  - Nr.3/2019
  - Nr.2/2019
  - Nr.1/2019
  - Supplement 1/2019
- 2018
  - Nr.4/2018
  - Nr.3/2018
  - Nr.2/2018
  - Nr.1/2018
  - Supplement 1/2018
  - Supplement 2/2018
  - Supplement 3/2018
- 2017
  - Nr.4/2017
  - Nr.3/2017
  - Nr.2/2017
  - Nr.1/2017
  - Supplement 1/2017
- 2016
  - Nr.4/2016
  - Nr.3/2016
  - Nr.2/2016
  - Nr.1/2016
  - Supplement 1/2016
- 2015
  - Nr.4/2015
  - Nr.3/2015
  - Nr.2/2015
  - Nr.1/2015
  - Supplement 1/2015
- 2014
  - Nr.4/2014
  - Nr.3/2014
  - Nr.2/2014
  - Nr.1/2014
  - Supplement 1/2014
- 2013
  - Nr.4/2013
  - Nr.3/2013
  - Nr.2/2013
  - Nr.1/2013
  - Supplement 1/2013
- 2012
  - Nr.4/2012
  - Nr.3/2012
  - Nr.2/2012
  - Nr.1/2012
  - Supplement 1/2012
- 2011
  - Nr.4/2011
  - Nr.3/2011
  - Nr.2/2011
  - Nr.1/2011
  - Supplement 1/2011
- 2010
  - Nr.4/2010
  - Nr.3/2010
  - Nr.2/2010
  - Nr.1/2010
  - Supplement 1/2010
- 2009
  - Nr.4/2009
  - Nr.3/2009
  - Nr.2/2009
  - Nr.1/2009
  - Supplement 1/2009
- 2008
  - Nr.4/2008
  - Nr.3/2008
  - Nr.2/2008
  - Nr.1/2008
  - Supplement 1/2008
- 2007
  - Nr.4/2007
  - Nr.3/2007
  - Nr.2/2007
  - Nr.1/2007
- 2006
  - Nr.4/2006
  - Nr.3/2006
  - Nr.2/2006
  - Nr.1/2006
- 2005
  - Nr.1/2005
Instructions for authors
Online applications
- Send an article
- Online payments
Editorial
About us
Links

ISSN online: 2284-5623

ISSN-L: 1841-6624

Rejection rate (2020): 75%

Journal Metrics

Impact Factor 0.5
Five Year Impact Factor 0.5
JCI 0.12

Top 10 downloaded articles - November 2024 -

Towards appropriate training f...	31
Recomandările naționale ale ...	28
Biomarkers of acute kidney inj...	23
A comprehensive review of glyc...	20
Agreement between different eG...	19
Investigation of cytokine chan...	19
Expressions of vascular endoth...	17
Role of Th1/Th2 imbalance medi...	16
Small patients, big challenges...	9
The frequency of EGFR gene mut...	8

Concept, Design & Programming
Dr. Adrian Man

Nr. 18(2)/2010

Fatal sepsis due to community-associated methicillin-resistant Staphylococcus aureus – a case report

Edit Székely, Liviu Sorin, Simona Marinescu, Erika Ungvári, Ákos Tóth , Judit Pászti

Abstract:

We present the case of a community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) infection, which led to a rapidly evolving fatal sepsis with necrotizing pneumonia in a four year old girl. The patient was admitted to the Mures County Emergency Clinical Hospital at 7:50 a.m. on the 15th of March 2007. A few days before presentation the girl had suffered a minor trauma of her left heel. According to clinical, biochemical and radiological findings, septic shock with cutaneous origin, cellulitis of the left heel and bilateral pneumonia were diagnosed. She received intravenous fluid resuscitation and large spectrum antibiotic therapy was started. Later that day, the patient’s condition deteriorated and she went on a cardiorespiratory stop and died at 03:25 p.m. On autopsy, bilateral necrotizing pneumonia was documented. MRSA was isolated from blood cultures. Based on epidemiological data and on phenotypical and molecular characterization, the strain was found to be a CA-MRSA harboring SCCmec type IV and Panton Valentine leukocidin genes which belonged to spa type t044. This was the first and so far only case of fatal sepsis occurring in our hospital due to CA-MRSA strain confirmed by means of molecular techniques. The dramatic rapidity of its evolution represents a major concern and demonstrates the extreme virulence and harming capacity of this type of CA-MRSA.

Keywords: pneumonia,Panton-Valentine leukocidin,bacterial typing

Download full text PDF
(646 KB)

Székely E, Sorin L, Marinescu S, Ungvári E, Á, Pászti J. Fatal sepsis due to community-associated methicillin-resistant Staphylococcus aureus – a case report. Rev Romana Med Lab. 2010;18(2):29-33