RRML - CALLY index, but not HALP score, is associated with mortality in cirrhosis patients

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Nr. 33(1)/2025 DOI:10.2478/rrlm-2025-0007

Research article

CALLY index, but not HALP score, is associated with mortality in cirrhosis patients

Günay Yıldız, Cihan Bedel, Ökkeş Zortuk, Fatih Selvi, Yusuf Karanci

Correspondence should be addressed to: Cihan Bedel

Abstract:

Background: Cirrhosis is a chronic liver disease that is characterized by inflammation and fibrosis, as well as liver dysfunction. The CALLY index and HALP score have recently provided crucial data in the diagnosis, follow-up, and prognosis of numerous diseases, particularly those of a malignant nature and those affecting the gastrointestinal system. The objective of this study was to ascertain whether the CALLY index and HALP score are appropriate indicators of mortality in patients with cirrhosis. Methods: This study was conducted retrospectively in patients with liver cirrhosis between 01.01.2022-01.10.2024. The HALP and CALLY scores were calculated from the blood samples taken from the patients at the time of admission. The in-hospital mortality status of the patients was recorded. The effects of the parameters on mortality were compared. Results: The study cohort comprised 235 participants, of whom 23 died. The median CALLY value was found to be 0.44 in patients who died and 1.19 in surviving patients. A significant decrease in the CALLY score was observed in patients who died (p=0.019). However, the HALP score did not show a significant difference in mortality between the two groups (p=0.262). Conclusions: Based on the results of our study, CALLY index is an easily applicable index that can be used as an indicator of mortality in cirrhosis patients, but the HALP score is not a suitable marker for this purpose.

Keywords: CALLY index, cirrhosis, HALP score, mortality

Received: 8.12.2024
Accepted: 26.1.2025
Published: 29.1.2025

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Yıldız G, Bedel C, Zortuk Ö, Selvi F, Karanci Y. CALLY index, but not HALP score, is associated with mortality in cirrhosis patients. Rev Romana Med Lab. 2025;33(1):29-34. DOI:10.2478/rrlm-2025-0007