RRML - Use of mathematical indices based on CBC data to identify patients with β thalassemia minor

Main page
News
RJLabM Credits
Archive
- Current issue
- Ahead of print
- List of published issues
- 2024
  - Nr.4/2024
  - Nr.3/2024
  - Nr.2/2024
  - Nr.1/2024
  - Supplement 1/2024
- 2023
  - Nr.4/2023
  - Nr.3/2023
  - Nr.2/2023
  - Nr.1/2023
  - Supplement 1/2023
- 2022
  - Nr.4/2022
  - Nr.3/2022
  - Nr.2/2022
  - Nr.1/2022
  - Supplement 1/2022
- 2021
  - Nr.4/2021
  - Nr.3/2021
  - Nr.2/2021
  - Nr.1/2021
- 2020
  - Nr.4/2020
  - Nr.3/2020
  - Nr.2/2020
  - Nr.1/2020
  - Supplement 1/2020
- 2019
  - Nr.4/2019
  - Nr.3/2019
  - Nr.2/2019
  - Nr.1/2019
  - Supplement 1/2019
- 2018
  - Nr.4/2018
  - Nr.3/2018
  - Nr.2/2018
  - Nr.1/2018
  - Supplement 1/2018
  - Supplement 2/2018
  - Supplement 3/2018
- 2017
  - Nr.4/2017
  - Nr.3/2017
  - Nr.2/2017
  - Nr.1/2017
  - Supplement 1/2017
- 2016
  - Nr.4/2016
  - Nr.3/2016
  - Nr.2/2016
  - Nr.1/2016
  - Supplement 1/2016
- 2015
  - Nr.4/2015
  - Nr.3/2015
  - Nr.2/2015
  - Nr.1/2015
  - Supplement 1/2015
- 2014
  - Nr.4/2014
  - Nr.3/2014
  - Nr.2/2014
  - Nr.1/2014
  - Supplement 1/2014
- 2013
  - Nr.4/2013
  - Nr.3/2013
  - Nr.2/2013
  - Nr.1/2013
  - Supplement 1/2013
- 2012
  - Nr.4/2012
  - Nr.3/2012
  - Nr.2/2012
  - Nr.1/2012
  - Supplement 1/2012
- 2011
  - Nr.4/2011
  - Nr.3/2011
  - Nr.2/2011
  - Nr.1/2011
  - Supplement 1/2011
- 2010
  - Nr.4/2010
  - Nr.3/2010
  - Nr.2/2010
  - Nr.1/2010
  - Supplement 1/2010
- 2009
  - Nr.4/2009
  - Nr.3/2009
  - Nr.2/2009
  - Nr.1/2009
  - Supplement 1/2009
- 2008
  - Nr.4/2008
  - Nr.3/2008
  - Nr.2/2008
  - Nr.1/2008
  - Supplement 1/2008
- 2007
  - Nr.4/2007
  - Nr.3/2007
  - Nr.2/2007
  - Nr.1/2007
- 2006
  - Nr.4/2006
  - Nr.3/2006
  - Nr.2/2006
  - Nr.1/2006
- 2005
  - Nr.1/2005
Instructions for authors
Online applications
- Send an article
- Online payments
Editorial
About us
Links

ISSN online: 2284-5623

ISSN-L: 1841-6624

Rejection rate (2020): 75%

Journal Metrics

Impact Factor 0.5
Five Year Impact Factor 0.5
JCI 0.12

Top 10 downloaded articles - November 2024 -

Towards appropriate training f...	31
Recomandările naționale ale ...	28
Biomarkers of acute kidney inj...	23
A comprehensive review of glyc...	20
Agreement between different eG...	19
Investigation of cytokine chan...	19
Expressions of vascular endoth...	17
Role of Th1/Th2 imbalance medi...	16
Small patients, big challenges...	9
The frequency of EGFR gene mut...	8

Concept, Design & Programming
Dr. Adrian Man

Nr. 8(3)/2007

Use of mathematical indices based on CBC data to identify patients with β thalassemia minor

Trefor Higgins, Yann Brierley, Annu Khajuria

Abstract:

The discrimination between thalassemic and non-thalassemic causes for microcytosis has important clinical significance. The incidence of β thalassemia trait in countries surrounding the Mediterranean and in Romania is high. In the absence of definitive DNA and quantification of HbA2 and HbF concentrations, the use of discrimination calculations based on complete blood count data has been proposed to identify patients with β thalassemia trait. Using ROC curves, the sensitivity and specificity of several widely used discrimination calculations are calculated. For patients who are iron replete the MCV, RDWI and Shine and Lal provide the best discrimination between normal and patients and those with β thalassemia.

Download full text PDF
(347 KB)

Higgins T, Brierley Y, Khajuria A. Use of mathematical indices based on CBC data to identify patients with β thalassemia minor. Rev Romana Med Lab. 2007;8(3):7-12