RRML - Proximal tubule dysfunction in renal diseases - diagnostic significance of proteomics and biomarkers

Main page
News
RJLabM Credits
Archive
- Current issue
- Ahead of print
- List of published issues
- 2024
  - Nr.4/2024
  - Nr.3/2024
  - Nr.2/2024
  - Nr.1/2024
  - Supplement 1/2024
- 2023
  - Nr.4/2023
  - Nr.3/2023
  - Nr.2/2023
  - Nr.1/2023
  - Supplement 1/2023
- 2022
  - Nr.4/2022
  - Nr.3/2022
  - Nr.2/2022
  - Nr.1/2022
  - Supplement 1/2022
- 2021
  - Nr.4/2021
  - Nr.3/2021
  - Nr.2/2021
  - Nr.1/2021
- 2020
  - Nr.4/2020
  - Nr.3/2020
  - Nr.2/2020
  - Nr.1/2020
  - Supplement 1/2020
- 2019
  - Nr.4/2019
  - Nr.3/2019
  - Nr.2/2019
  - Nr.1/2019
  - Supplement 1/2019
- 2018
  - Nr.4/2018
  - Nr.3/2018
  - Nr.2/2018
  - Nr.1/2018
  - Supplement 1/2018
  - Supplement 2/2018
  - Supplement 3/2018
- 2017
  - Nr.4/2017
  - Nr.3/2017
  - Nr.2/2017
  - Nr.1/2017
  - Supplement 1/2017
- 2016
  - Nr.4/2016
  - Nr.3/2016
  - Nr.2/2016
  - Nr.1/2016
  - Supplement 1/2016
- 2015
  - Nr.4/2015
  - Nr.3/2015
  - Nr.2/2015
  - Nr.1/2015
  - Supplement 1/2015
- 2014
  - Nr.4/2014
  - Nr.3/2014
  - Nr.2/2014
  - Nr.1/2014
  - Supplement 1/2014
- 2013
  - Nr.4/2013
  - Nr.3/2013
  - Nr.2/2013
  - Nr.1/2013
  - Supplement 1/2013
- 2012
  - Nr.4/2012
  - Nr.3/2012
  - Nr.2/2012
  - Nr.1/2012
  - Supplement 1/2012
- 2011
  - Nr.4/2011
  - Nr.3/2011
  - Nr.2/2011
  - Nr.1/2011
  - Supplement 1/2011
- 2010
  - Nr.4/2010
  - Nr.3/2010
  - Nr.2/2010
  - Nr.1/2010
  - Supplement 1/2010
- 2009
  - Nr.4/2009
  - Nr.3/2009
  - Nr.2/2009
  - Nr.1/2009
  - Supplement 1/2009
- 2008
  - Nr.4/2008
  - Nr.3/2008
  - Nr.2/2008
  - Nr.1/2008
  - Supplement 1/2008
- 2007
  - Nr.4/2007
  - Nr.3/2007
  - Nr.2/2007
  - Nr.1/2007
- 2006
  - Nr.4/2006
  - Nr.3/2006
  - Nr.2/2006
  - Nr.1/2006
- 2005
  - Nr.1/2005
Instructions for authors
Online applications
- Send an article
- Online payments
Editorial
About us
Links

ISSN online: 2284-5623

ISSN-L: 1841-6624

Rejection rate (2020): 75%

Journal Metrics

Impact Factor 0.5
Five Year Impact Factor 0.5
JCI 0.12

Top 10 downloaded articles - January 2025 -

Romanian Review of Laboratory ...	15
Investigation of cytokine chan...	12
Recomandările naționale ale ...	9
Correlation between fecal biom...	9
A comprehensive review of Prof...	8
Biomarkers of acute kidney inj...	8
Implementing essential require...	7
Expressions of vascular endoth...	7
COVID-19 or systemic lupus ery...	7
Study of the antimicrobial act...	6

Concept, Design & Programming
Dr. Adrian Man

Nr. 20(2)/2012

Proximal tubule dysfunction in renal diseases - diagnostic significance of proteomics and biomarkers

Ligia Petrica, A. Gluhovschi, Cristina Gluhovschi, Florica Gadalean, C. Balgradean, Cristina Groza, Silvia Velciov

Abstract:

At present time, clinical practice requires advanced studies of plasma and urinary proteomics which should allow the identification, selection, and implementation of plasma and urinary biomarkers useful in the diagnosis of acute and chronic renal diseases, as well as of drug-induced nephrotoxicity. The importance of these biomarkers also resides in their prognostic value and the posibility of their repeated and dinamic assessment, in order to detect early the progression of an acute renal disease to chronic kidney disease, and of the later one to its final stages.In the present paper urinary biomarkers and proteomics, and their application in the accurate diagnosis of tubular lesions in various settings, (such as early diabetic nephropathy, acute kidney injury, glomerular nephropathies, polycystic kidney disease, renal transplantation, Balkan endemic nephropathy, and preeclampsia), are discussed in view of the clinical expertise of the authors in this field.

Keywords: biomarkers,proteomics,tubular lesions

Download full text PDF
(148 KB)

Petrica L, Gluhovschi A, Gluhovschi C, Gadalean F, Balgradean C, Groza C, et al. Proximal tubule dysfunction in renal diseases - diagnostic significance of proteomics and biomarkers. Rev Romana Med Lab. 2012;20(2):97-107