RRML - Diabetes mellitus: in search of an improved classification and treatment algorithm

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Nr. 24(1)/2016 DOI:10.1515/rrlm-2016-0001

Editorial

Diabetes mellitus: in search of an improved classification and treatment algorithm

Simona Cernea, Avivit Cahn

Correspondence should be addressed to: Simona Cernea

Abstract:

Our current clinical doctrine and practice is based upon a classification of diabetes which relies mainly on some clinical manifestations/criteria, rather than markers of the pathophysiological mechanisms of the disease. An improved classification based on such biological markers (i.e. of insulin resistance, beta cell dysfunction, autoimmunity) may assist in clinical decision and may offer the opportunity of an optimized therapeutic strategy. We address here some important questions that have not yet been clarified, e.g. which markers/indicators best define the main pathogenic mechanisms of the disease in a patient with diabetes and what threshold values are relevant for this purpose.

Keywords: diabetes mellitus, classification, biological markers, pathophysiologic mechanisms

Received: 21.10.2015
Accepted: 15.12.2015
Published: 24.12.2015

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Cernea S, Cahn A. Diabetes mellitus: in search of an improved classification and treatment algorithm. Rev Romana Med Lab. 2016;24(1):9-20. DOI:10.1515/rrlm-2016-0001