RRML - Human Leucocytes Antigens Alleles and the Evolution of the Infection with the Human Immunodeficiency Virus Type 1

Main page
News
RJLabM Credits
Archive
- Current issue
- Ahead of print
- List of published issues
- 2023
  - Nr.2/2023
  - Nr.1/2023
- 2022
  - Nr.4/2022
  - Nr.3/2022
  - Nr.2/2022
  - Nr.1/2022
  - Supplement 1/2022
- 2021
  - Nr.4/2021
  - Nr.3/2021
  - Nr.2/2021
  - Nr.1/2021
- 2020
  - Nr.4/2020
  - Nr.3/2020
  - Nr.2/2020
  - Nr.1/2020
  - Supplement 1/2020
- 2019
  - Nr.4/2019
  - Nr.3/2019
  - Nr.2/2019
  - Nr.1/2019
  - Supplement 1/2019
- 2018
  - Nr.4/2018
  - Nr.3/2018
  - Nr.2/2018
  - Nr.1/2018
  - Supplement 1/2018
  - Supplement 2/2018
  - Supplement 3/2018
- 2017
  - Nr.4/2017
  - Nr.3/2017
  - Nr.2/2017
  - Nr.1/2017
  - Supplement 1/2017
- 2016
  - Nr.4/2016
  - Nr.3/2016
  - Nr.2/2016
  - Nr.1/2016
  - Supplement 1/2016
- 2015
  - Nr.4/2015
  - Nr.3/2015
  - Nr.2/2015
  - Nr.1/2015
  - Supplement 1/2015
- 2014
  - Nr.4/2014
  - Nr.3/2014
  - Nr.2/2014
  - Nr.1/2014
  - Supplement 1/2014
- 2013
  - Nr.4/2013
  - Nr.3/2013
  - Nr.2/2013
  - Nr.1/2013
  - Supplement 1/2013
- 2012
  - Nr.4/2012
  - Nr.3/2012
  - Nr.2/2012
  - Nr.1/2012
  - Supplement 1/2012
- 2011
  - Nr.4/2011
  - Nr.3/2011
  - Nr.2/2011
  - Nr.1/2011
  - Supplement 1/2011
- 2010
  - Nr.4/2010
  - Nr.3/2010
  - Nr.2/2010
  - Nr.1/2010
  - Supplement 1/2010
- 2009
  - Nr.4/2009
  - Nr.3/2009
  - Nr.2/2009
  - Nr.1/2009
  - Supplement 1/2009
- 2008
  - Nr.4/2008
  - Nr.3/2008
  - Nr.2/2008
  - Nr.1/2008
  - Supplement 1/2008
- 2007
  - Nr.4/2007
  - Nr.3/2007
  - Nr.2/2007
  - Nr.1/2007
- 2006
  - Nr.4/2006
  - Nr.3/2006
  - Nr.2/2006
  - Nr.1/2006
- 2005
  - Nr.1/2005
Instructions for authors
Online applications
- Send an article
- Online payments
Editorial
About us
Links

ISSN online: 2284-5623

ISSN-L: 1841-6624

Rejection rate (2020): 75%

Journal Metrics

Impact Factor 0.493
Five Year Impact Factor 0.531
SNIP 0.373
JCI 0.17

Top 10 downloaded articles - June 2023 -

Screening of a novel BRCA2 mut...	15
The evaluation of a diagnostic...	3
Gene polymorfism of angiotensi...	2
Serum leptin levels in obese c...	2
Versant HCV Genotype 2.0 Assay...	2
Comparison of two analytical m...	2
Renal dysfunction at hospital ...	2
Comparative analysis of GSTM1/...	2
Inhibitory effects on the HMG-...	2
GJB2 and GJB6 genes mutations ...	2

Concept, Design & Programming
Dr. Adrian Man

Nr. 18(2)/2010

Human Leucocytes Antigens Alleles and the Evolution of the Infection with the Human Immunodeficiency Virus Type 1

Dragos Florea, Simona Paraschiv, Mihaela Fratila, Dan Otelea

Abstract:

Differences in host susceptibility to infectious diseases are well documented. While the mechanisms underlying these differences are far from elucidated, recent progress in the genomics of pathogen-host interactions has increased our understanding of the phenomenon. An increasing number of studies demonstrate that the major histocompatibility complex molecules modulate the overall susceptibility to HIV infection, the risk of vertical transmission from mother to child, the risk of horizontal transmission in HIV discordant couples, the rate of progression to an AIDS-defining illness, and the risk of severe reactions to antiretroviral treatment. These data can influence new diagnostic, therapeutic and prophylactic strategies.

Keywords: HIV,elite supressors,AIDS progression

Download full text PDF
(117 KB)

Florea D, Paraschiv S, Fratila M, Otelea D. Human Leucocytes Antigens Alleles and the Evolution of the Infection with the Human Immunodeficiency Virus Type 1. Rev Romana Med Lab. 2010;18(2):7-17