RRML - Introduction on the human urinary proteome
AMLR

ISSN online: 2284-5623

ISSN-L: 1841-6624

Impact factor (2020): 1.027

Rejection rate (2020): 75%

Română English


Clarivate analytics (ISI) Impact factor


Advanced search


Top 10 downloaded articles
- May 2022 -
 
Approaching Risk Management in... 16
Screening of a novel BRCA2 mut... 14
Romanian Review of Laboratory ... 9
Matrix-assisted Laser Desorpti... 9
Proposal of a prediction model... 9
The evaluation of a diagnostic... 8
The evaluation of the preanaly... 7
Associations of serum expressi... 7
Downregulation of hsa-miR-4328... 7
Clinical significance of serum... 6

Log in

Concept, Design & Programming
Dr. Adrian Man

   
 
Nr. 10(1)/2008
XML
TXT

Introduction on the human urinary proteome

Ileana Funduc


Abstract:

Human urine is one of the most used biofluids for proteomics study, because of noninvasiveness and simplicity of specimen collection. The obtained results give the possibility to study biomarkers for kidney diseases as well as other disorders that may have systemic alterations in the metabolic and biochemical profiles that can affect urinary protein excretion. The study presents the stages by which the urine passes to obtain human urinary proteome: collection, concentration with chemical or physical methods, bidimensional or capillary electrophoresis or liquid chromatography and finally detection and identification of proteins by mass spectrometry. Future directions are focused not only on renal physiology, path physiology and biomarkers discovery, but also on development of new target therapies.

 
  PDF Download full text PDF
(70 KB)
     
 
How to cite
Funduc I. Introduction on the human urinary proteome. Rev Romana Med Lab. 2008;10(1):7-11