RRML - Impact of preanalytical variables on the quality of laboratory results

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Nr. 4(3)/2006

Impact of preanalytical variables on the quality of laboratory results

Minodora Dobreanu, Andrea Fodor, Anca Bacârea

Abstract:

The aim of a clinical laboratory test is to determine the true value of a diagnostically relevant analyte in a body fluid at the sampling time by in vitro analysis. This assumes that the composition of the samples taken for this purpose does not change during the preanalytical phase (sampling, transportation, storage, sample preparation). Whereas the laboratorian may be aware of the possibility of an analytical interference, clinicians are largely unaware of these effects and the available resources to help them interpret test value correctly. When this information is not given with the result, clinicians may missinterpret test values and take an inappropriate action with their patients.

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Dobreanu M, Fodor A, Bacârea A. Impact of preanalytical variables on the quality of laboratory results. Rev Romana Med Lab. 2006;4(3):63-72